Published on Aug 14, 2020
Revision
24. Kawasaki Disease

It affects children under the age of 6 years old with severe disease often associated with children under 1 year old.

Diagnostic criteria:. 5-day fever PLUS four of the following…
➔ Bilateral conjunctivitis
➔ Cervical lymph node >1.5cm
➔ Polymorphous exanthem
➔ Cracked lips/strawberry tongue
➔ Erythema/oedema/peeling of the hands/feet
Other features include BCG scar inflammation, raised CRP, thrombocytosis and irritability without CNS infection.
Beware:. diagnosis can be made before Day 5 of fever if clinical signs suggestive. Also if just 2-3 criteria present, consider incomplete Kawasaki.

Complications include:.
● Coronary aneurysms (causing thrombosis, MI and tamponade)
● Myocarditis
● Bleeding (due to aspirin) 

Consider echo EARLY in diagnosis

Treatment is with high-dose aspirin, IV immunoglobulin & Proton Pump Inhibitors.